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HA5® Rejuvenating Hydrator 2 Oz.

HA5® Rejuvenating Hydrator 2 Oz.

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Provides immediate smoothing in the appearance of fine lines and wrinkles, and supports the skin's natural ability to retain moisture resulting in radiant, rejuvenated tone and texture.

Appropriate for all skin types.

Before & After Pictures

Baseline vs 15 Minutes, Male, Age 63

Baseline vs 8 Weeks, Female, Age 50

Unretouched photos taken with parallel-polarized lighting. Individual results may vary. For 15-minute results, the product was left on the subject’s face. For 8-week results, no product on the subject's face. Data on file at SkinMedica®.

Patient Satisfaction

96% of subjects

agreed that immediately after applying HA5 it made their skin feel smooth and soft*.

91% of subjects

agreed that after 8 weeks of twice-daily use, HA5 made their skin feel "more refreshed” and “moisturized"*.

100% of subjects n = 23

agreed that HA5 was convenient and works well with other products*. 

*Narurkar VA, Fabi SG, Bucay VW, et al. A New Approach in Topical Hyaluronic Acid; Going Beyond Instant Benefits to Restore Epidermal HA Homeostasis. J Drug Dermatol. 2016:15(1 Suppl2);s24-s37.

Key Benefits of HA5®

HA5® delivers both immediate and long-term benefits

Instantly smoothes the appearance of fine lines and wrinkles

Immediate hydration

Improves the appearance of skin texture and roughness



Exponentially Smooth

HA5® supports the skin’s ability to replenish its own hyaluronic acid (HA) for overall skin health. HA5® has a proprietary mix of five HA forms that smooth the skin, thereby decreasing the appearance of fine lines and wrinkles. The 5 HA's work synergistically to provide immediate smoothing and continuous hydration throughout the day.

When to Apply

Apply twice daily—in the morning and at night—after cleansing, toning, and treating your skin. Apply before you moisturize and apply SPF (sun protection).

Where to Apply

Apply to face, neck, and chest, or any area where fine lines and wrinkles primarily exist.

How to Apply

Because HA5® is a "water-loving" substance, wet your fingertips prior to applying HA5® to your skin. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.

What’s Inside

Key Ingredients

VITISENSCE® Technology:

A SkinMedica® exclusive technology that harnesses potent antioxidants found in Vitis Flower Stem Cell Extract, Peptide Complex to support rejuvenation and hydration, and Polysaccharides from French Polynesia for healthy-looking skin—all working to support skin's ability to replenish its own hyaluronic acid for overall skin health.

Specialty Ingredients

A proprietary mix of 5 types of HA that smooth the skin, thereby decreasing the appearance of fine lines and wrinkles.

Time Release HA:

A SkinMedica® proprietary ingredient for sustained release of HA

Sodium Hyaluronate:

For immediate hydration

Uncross-linked HA:

For smoothness and hydration

Nano HA:

Soothes skin

Cross-Linked HA:

Provides long-lasting hydration for up to 8 hours